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The Turkish Journal of Invasive Cardiology/Contents
VOLUME 7 - NUMBER 2 - MAY 2003

ImmedIate and 6 months follow-up results of dIrect stentIng

Effects of C-reactIve proteIn levels measured before after percutaneous coronary Inter-ventIon on early and 6.month follow-up results

Effects of dIfferent cardIoversIon technIques on atrIal mechanıcal functıons In patIents wIth atrIal fIbrIllatIon

DIstal protectIon durIng percutaneous InterventIon In patIents wIth acute myocardIal InfarctIon

Left maIn coronary artery stenosIs

HomocysteIne and cardIovascular rIsk

A case of ascendent aortIc pseudoaneursym after perIcardIectomy

Acute coronary dıssectIon durIng  coronary angIography lIkely due to rapId dye InjectIon

A new technIque tor treatment of coronary musculer brıdge causıng myocardıa IschemIa

SIngle coronary artery

 

ImmedIate and 6 months follow-up results of dIrect stentIng

Akdemir R, Gündüz H, Duran S, Uyan C.

Intracoronary stent implantation, without predilation, is a developing technique. İt has the potential to have a favorable impact on procedure cost by reducing the number of devices used, contrast administered, and procedure time. Restenosis may be reduced by direct stenting compared with stenting after pre-dilatation. We conducted this study to evaiuate the immediate and sixth months results of direct stenting with ephesos stent (Medistar, Türkiye). 55patients (male 45 (81.8%), female 10 (18.2%) and age 57.8±11.4) who had direct stent implantation (58 stents for 58 lesions in 55 patients) included to the study. There was not any death, acute Mİ or need for emergent CABG vvithin first 48 hours. One patient had an acute MI and re-revascularization in the first week due to discontiniouing of ticlopidin. Procedural success was 94.8%. There was not any death, acute MI or re-revaskülarization vvithin 30 days. Ali patients were undervvent angiographic evaluation at the sixth month's follow-up. Stent was patent in 45 patient (81.5%) and there were critical in-stent restenosis in 10 patients (18.5%). Our findings suggest that direct stenting is a new and safe methode in selected conditions.

Key Words: Direct stenting, Restenosis, Ephesos stent

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Effects of C-reactIve proteIn levels measured before after percutaneous coronary Inter-ventIon on early and 6.month follow-up results

Aytekin S, Çatakoğlu A.B, Aytekin V, Kocazeybek B, Demiroğlu İ.C.C, Demiroğlu C.

The role of inflammation in the pathogenesis of atherosclerosis has been discussed for a long time. C-reac¬tive protein (CRP) is an acute phase reactant and thus a marker for systemic inflammation . İn this study, blood samples for CRP is taken from the patients (pts) with different clinical presentations, just before the percutaneous coro¬nary intervention (PCI) and in the 24th hour of the procedure. VVe evaluated the effects of CRP levels on the early and late term majör adverse cardiac event (MACE), the predictive value of CRP on MACE and the effect of PCI on CRP levels after the procedure. 116 Sequential pts who have PCI for one lesion is included in the study. Pts vvith mul-tivessel PCI, left ventricular ejection fraction lower than 30 %, totally occluded lesions, left bundle branch block, inter-current inflammatory conditions known to be associated vvith an acute phase response are excluded.

A majör adverse cardiac event (MACE) was defined as myocardial infarction (Q wave or Non-Q wave), need for repeat target vessel revascularization or cardiovascular death that occurred follovving PCI. End points were evaluated at the end of in hospital period, 1st, 3rd and 6th month.

CRP tevel was < 0.5 mg/dl in 63 (54%) and > 0.5 mg/dl in 53 (46%) pts. There were no significant diffe-rences betvveen two groups up to 30 days. At the end of 3rd and 6th month the difference betvveen two groups were significant according to the MACE [1.6% - 11% , (p<0.05) and 9.5%- 24.5% (p<0.05) sequentially]. The positive predictive value of CRP was 24% and negative predictive value was 90.5% in 6th month. As the CRP levels were sig-nificantly increased in ali groups of pts vvith different clinical presentation after PCI ; it had no influence on MACE at the end of 6th month.

MACE was higher in the pts who have higher CRP levels before PCI, in the long term follovv up period. The negative predictive value of CRP was significantly high in both the early and the late follovv up period. PCI itself increases the CRP levels. These results shows us that CRP levels are independently important among the other risk factors and it must be measured before PCI,   to predict the risc group of the pts for MACE.

Key Words: C-reactive protein,  Percutaneous coronary intervention, Follow-up

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Effects of dIfferent cardIoversIon technIques on atrIal mechanıcal functıons In patIents wIth atrIal fIbrIllatIon

Yeşilbursa D, Odabaşı A.Y, Serdar O.A, Coşkun Ş, Saltan Y, Çordan J.

Atrial fibrillation (AF) causes atrial dilation. Conversion of AF to sinüs rhythm results in a transient mechanical dys-function of atria (atrial stunning). By using echocardiography this study examined the effects of different modes of car¬dioversion on left atrial size and functions in patients with AF.

A total number of 32 patients were enrolled in the study in whom sinüs rhythm was maintained pharmacologically in 17, spontaneously in 10 and electrically in 5 of them. AH patients were underwent transthoracic echocardiography before, 4 hours, 24 hours, 7 days and 30 days after cardioversion.

A significant decrease in left atrial size were detected in ali three groups in which left atrias were dilated before car¬dioversion. Although there were no significant changes in mitral E wave velocities and E wave velocity time integrals during the 30 days follow up period, A wave velocities and A wave velocity time integrals showed a significant increase. There were no significant differences in groups of spontaneous, electrical and pharmacological cardioversion in 24 hour hours, 7 days and 30 days after cardioversion when compared for the development of atrial stunning. Similarly to the mitral valve flow patterns, peak A wave velocity and A wave velocity time integrals recorded from the tricuspit valve measurements shovved significant increase after cardioversion. Hovvever it was seen the recovery of the mechanical functions of the right atrium was earlier than the left atrium.

As a result; it was shown that the delay of the left atrial mechanical functions was not related with the cardiover¬sion method and besides the left atrial mechanical dysfunction, right atrial mechanical dysfunction had also occured, but the recovery of the right atrial mechanical activity was earlier.

Key Words: Atrial fibrillation, Cardioversion, Atrial stunning

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DIstal protectIon durIng percutaneous InterventIon In patIents wIth acute myocardIal InfarctIon

İlkay E, Yavuzkır M.

Balloon angioplasty for treatment of acute myocardial infarction (AMI) may cause thrombus dislocation, distal embolisation and in-situ thrombus formation. The studies made by contrast echocardiography, positron emmission tomography and complex sintigraphy were showed that myocardial methabolism and perfusion were not normal even TIMl-lll flow was achieved by interventional. The most important mortality predictor of Mİ after invasive treatment is the abscence of distal flow (TİMİ O/l). İn contrast, the degree of myocardial blush is more sensitive predictor of mortality than TIMl-lll flow in the case of TIMl-lll flow is established. İt was throught that myocardial perfusion can be increased by preventing the distal embolisation. The first studies made in coronary vessels were encouraging.

Distal protection can be suggested to proximal lesions with high thrombus content currently. Randomised tri-als are needed for rutine application.

Key Words: AMI, Distal protection, PCI

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Left maIn coronary artery stenosIs

Selçuk H, Selçuk T.M, Çelenk M.K, Korkmaz Ş.

Left main coronary artery (LMCA) stenosis is a condition of high prognostic significance, occurring must commonly as a result of atherosclerosis. Fifty percent or higher narrovving of the LMCA is encountered in 3-5 % of coro¬nary arteriography procedures.

While the majority of patients with LMCA disease have a history of unstable coronary syndromes and/ or myocar¬dial infarction, there are completely asymptomatic individuals as well. LMCA lesions can be broadly classified as ostial and non-ostial. Ostial lesions are usually discrete and eccentric, and are more frequently seen in women.

Complications related to catheterization procedures are significantly more common in the setting of LMCA steno¬sis. Development of procedural adverse events are knovvn to be influenced by several factors, such as congestive heart failure, systemic hypertension, female gender and distance betvveen catheter tip and lesion. Post procedural mortality have also been related to a number of clinical features, namely, advanced age, new- onset angina, low ejection fraction and high left ventricular end-diastolic pressure.

Acut occlusion of the LMCA is a rare but clinically drastic event with a very high mortality. İt is imperetive that reperfusion be provided in this patients as rapidly as possible. On the other hand chronic total occlusion of the LMCA has a quite varied clinical picture and occurs in 0,04- 0,042 % of patients undergoing coronary angiography characteristi-cally individuals with chronic LMCA obstruction are highly dependent on an extensive collateral circulation that perfu-ses the LMCA supplied areas from the right coronary artery.

Coronary artery by-pass grafting is the therapeutic modality of choice in LMCA stenosis. For patient in whom surgery could not be undertaken, percutaneos coronary balloon angioplasty with or without stenting has been succesfully performed. İn particular, stenting has been demonstrated to be superior to sole application of angioplasty in terms of procedural success moreover, stent placement is considered to have a favorable influnce on early term mortality rates.

Key Words: Left main coronary artery, Stenosis, Coroner angiography

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HomocysteIne and cardIovascular rIsk

Özaydın M, Doğan A, Ergene O.

Homocysteine is an amino acid present in the plasma and it is regarded as a risk factor for the development of coronary artery disease (CAD) by means of endothelial dysfunction. Folat, vitamin B6 and vitamin B12 can decrease plasma homocystein levels and improve endothelial dysfunction. The association betvreen hyperhomocysteinemia and CAD or restenosis after percutaneous coronary interventions and vvhether decreasing plasma homocysteine levels can reduce these risks remains controversial and different studies show different results.

Key Words: Homocysteine, Coronary artery disease, Restenosis

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A case of ascendent aortIc pseudoaneursym after perIcardIectomy

Emir M, Uncu H, Çağlı K, Altıntaş G, Şener E, Taşdemir O.

We present a case of a 18-year-ald patient with a mass pulsatil near the jugulum and had the sympthoms (eg; dispnea) 2 years after pericardiectomy: because of constrictive pericarditis.

Physical examination findings was only 2/6° systolic sufl at the aortic localization. Diagnosis was confirmed with the aid of two-dimensional echocardiography annd aortography.a 8x8 cm diameter of pseudoaneursym at anterior surface of ascending aorta and proxmity of tr.brachiocephalicus vvhich had calcification around it was found by echo and aortography.

We planed surgery for treatment. The formation of a pseudoaneursym following pericardiectomy is a rare complication. So we present this case report. Nowwe know that, ascending aorta pseudoaneursym follovving pericardiec¬tomy can be generated as a complication. VVe suggest that a patient undergo pericardiectomy has to be evaluated carefully because of pseudoaneursym formation.

Key Words: Ascenden aort pseudoaneurysm, Pseudoaneurysm, Postpericardiectomy

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Acute coronary dıssectIon durIng  coronary angIography lIkely due to rapId dye InjectIon

Erikçi H, Gündüz H, Binak E, Akdemir R, Kanat M, Kurtoğlu N, Keser N, Dindar İ, Uyan C.

Coronary artery dissections during coronary angiography are rare. Prompt recognition and subsequent emergency interventions are essential, especially when significant amount of myocardium is threatened.

Key Words: Coronary artery dissection, Dissection, Coronary angiography

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A new technIque tor treatment of coronary musculer brıdge causıng myocardıa IschemIa

Cin V.G, Pekdemir H, Akkuş N, Katırcıbaşı T.

Myocardial bridge is a congenital coronary anomaly vvhich causes sudden cardiac death, cardiac arrythmias myocardial ischemia and infarction. Recently, direct stent deployment within myocardial bridges which cause serious ischemia is getting vvidely used. İn this manuscript, primary stent deployment and its result in a patient who has twc symptomatic myocardial bridges in left anterior descending artery is discussed below with literatüre.

Key Words: Myocardial bridge, Intracoronary stent

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SIngle coronary artery

Akdeniz B, Kırımlı Ö, Aytekin D, Badak Ö.

The frequency of anamolous origin of coronary arteries in angiopgraphic series was reported 0,6%-1,6% Single coronary artery is a rare congenital abnormality of the coronary arteries where only one coronary artery arise from the aortic trunk by a single coronary ostium, supplying the entire heart. The incidence of single coronary artery abnormalities varies between 0,024%-0,044% and particularly Ula type is very rare. İn this article We present a case with single coronary artery in vvhom coronary angiography was normal and literatüre was reviewed.

Key Words: Coronary artery abnormalities, Single coronary artery, Coronary angiography

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