ImmedIate and 6 months follow-up results
of dIrect stentIng
Akdemir R,
Gündüz H, Duran S, Uyan C.
Intracoronary stent
implantation, without predilation, is a developing technique. İt has the
potential to have a favorable impact on procedure cost by reducing the
number of devices used, contrast administered, and procedure time.
Restenosis may be reduced by direct stenting compared with stenting after
pre-dilatation. We conducted this study to evaiuate the immediate and sixth
months results of direct stenting with ephesos stent (Medistar, Türkiye).
55patients (male 45 (81.8%), female 10 (18.2%) and age 57.8±11.4) who had
direct stent implantation (58 stents for 58 lesions in 55 patients) included
to the study. There was not any death, acute Mİ or need for emergent CABG
vvithin first 48 hours. One patient had an acute MI and re-revascularization
in the first week due to discontiniouing of ticlopidin. Procedural success
was 94.8%. There was not any death, acute MI or re-revaskülarization vvithin
30 days. Ali patients were undervvent angiographic evaluation at the sixth
month's follow-up. Stent was patent in 45 patient (81.5%) and there were
critical in-stent restenosis in 10 patients (18.5%). Our findings suggest
that direct stenting is a new and safe methode in selected conditions.
Key Words: Direct stenting, Restenosis, Ephesos
stent
The
role of inflammation in the pathogenesis of atherosclerosis
has been discussed for a long time. C-reac¬tive protein (CRP)
is an acute phase reactant and thus a marker for systemic
inflammation . İn this study, blood samples for CRP is taken
from the patients (pts) with different clinical
presentations, just before the percutaneous coro¬nary
intervention (PCI) and in the 24th hour of the procedure.
VVe evaluated the effects of CRP levels on the early and
late term majör adverse cardiac event (MACE), the predictive
value of CRP on MACE and the effect of PCI on CRP levels
after the procedure. 116 Sequential pts who have PCI for one
lesion is included in the study. Pts vvith mul-tivessel PCI,
left ventricular ejection fraction lower than 30 %, totally
occluded lesions, left bundle branch block, inter-current
inflammatory conditions known to be associated vvith an
acute phase response are excluded.
A majör adverse cardiac event (MACE)
was defined as myocardial infarction (Q wave or Non-Q wave),
need for repeat target vessel revascularization or
cardiovascular death that occurred follovving PCI. End
points were evaluated at the end of in hospital period, 1st,
3rd and 6th month.
CRP tevel was < 0.5 mg/dl in 63 (54%)
and > 0.5 mg/dl in 53 (46%) pts. There were no significant
diffe-rences betvveen two groups up to 30 days. At the end
of 3rd and 6th month the difference betvveen two groups were
significant according to the MACE [1.6% - 11% , (p<0.05) and
9.5%- 24.5% (p<0.05) sequentially]. The positive predictive
value of CRP was 24% and negative predictive value was 90.5%
in 6th month. As the CRP levels were sig-nificantly
increased in ali groups of pts vvith different clinical
presentation after PCI ; it had no influence on MACE at the
end of 6th month.
MACE was higher in the pts who have
higher CRP levels before PCI, in the long term follovv up
period. The negative predictive value of CRP was
significantly high in both the early and the late follovv up
period. PCI itself increases the CRP levels. These results
shows us that CRP levels are independently important among
the other risk factors and it must be measured before PCI,
to predict the risc group of the pts for MACE.
Effects of dIfferent cardIoversIon technIques on atrIal
mechanıcal functıons In patIents wIth atrIal fIbrIllatIon
Yeşilbursa D, Odabaşı A.Y, Serdar O.A, Coşkun Ş, Saltan Y,
Çordan J.
Atrial
fibrillation (AF) causes atrial dilation. Conversion of AF to sinüs rhythm
results in a transient mechanical dys-function of atria (atrial stunning).
By using echocardiography this study examined the effects of different modes
of car¬dioversion on left atrial size and functions in patients with AF.
A total number of 32 patients were enrolled in the
study in whom sinüs rhythm was maintained pharmacologically in 17,
spontaneously in 10 and electrically in 5 of them. AH patients were
underwent transthoracic echocardiography before, 4 hours, 24 hours, 7 days
and 30 days after cardioversion.
A significant decrease in left atrial size were
detected in ali three groups in which left atrias were dilated before car¬dioversion.
Although there were no significant changes in mitral E wave velocities and E
wave velocity time integrals during the 30 days follow up period, A wave
velocities and A wave velocity time integrals showed a significant increase.
There were no significant differences in groups of spontaneous, electrical
and pharmacological cardioversion in 24 hour hours, 7 days and 30 days after
cardioversion when compared for the development of atrial stunning.
Similarly to the mitral valve flow patterns, peak A wave velocity and A wave
velocity time integrals recorded from the tricuspit valve measurements
shovved significant increase after cardioversion. Hovvever it was seen the
recovery of the mechanical functions of the right atrium was earlier than
the left atrium.
As a result; it was shown that the delay of the left
atrial mechanical functions was not related with the cardiover¬sion method
and besides the left atrial mechanical dysfunction, right atrial mechanical
dysfunction had also occured, but the recovery of the right atrial
mechanical activity was earlier.
DIstal
protectIon durIng percutaneous InterventIon In patIents wIth
acute myocardIal InfarctIon
İlkay E,
Yavuzkır M.
Balloon angioplasty for treatment of acute myocardial
infarction (AMI) may cause thrombus dislocation, distal
embolisation and in-situ thrombus formation. The studies
made by contrast echocardiography, positron emmission
tomography and complex sintigraphy were showed that
myocardial methabolism and perfusion were not normal even
TIMl-lll flow was achieved by interventional. The most
important mortality predictor of Mİ after invasive treatment
is the abscence of distal flow (TİMİ O/l). İn contrast, the
degree of myocardial blush is more sensitive predictor of
mortality than TIMl-lll flow in the case of TIMl-lll flow is
established. İt was throught that myocardial perfusion can
be increased by preventing the distal embolisation. The
first studies made in coronary vessels were encouraging.
Distal protection can be suggested to
proximal lesions with high thrombus content currently.
Randomised tri-als are needed for rutine application.
Left main coronary artery (LMCA) stenosis is a condition of
high prognostic significance, occurring must commonly as a
result of atherosclerosis. Fifty percent or higher
narrovving of the LMCA is encountered in 3-5 % of coro¬nary
arteriography procedures.
While the majority of patients with
LMCA disease have a history of unstable coronary syndromes
and/ or myocar¬dial infarction, there are completely
asymptomatic individuals as well. LMCA lesions can be
broadly classified as ostial and non-ostial. Ostial lesions
are usually discrete and eccentric, and are more frequently
seen in women.
Complications related to
catheterization procedures are significantly more common in
the setting of LMCA steno¬sis. Development of procedural
adverse events are knovvn to be influenced by several
factors, such as congestive heart failure, systemic
hypertension, female gender and distance betvveen catheter
tip and lesion. Post procedural mortality have also been
related to a number of clinical features, namely, advanced
age, new- onset angina, low ejection fraction and high left
ventricular end-diastolic pressure.
Acut occlusion of the LMCA is a rare
but clinically drastic event with a very high mortality. İt
is imperetive that reperfusion be provided in this patients
as rapidly as possible. On the other hand chronic total
occlusion of the LMCA has a quite varied clinical picture
and occurs in 0,04- 0,042 % of patients undergoing coronary
angiography characteristi-cally individuals with chronic
LMCA obstruction are highly dependent on an extensive
collateral circulation that perfu-ses the LMCA supplied
areas from the right coronary artery.
Coronary artery by-pass grafting is the
therapeutic modality of choice in LMCA stenosis. For patient
in whom surgery could not be undertaken, percutaneos
coronary balloon angioplasty with or without stenting has
been succesfully performed. İn particular, stenting has been
demonstrated to be superior to sole application of
angioplasty in terms of procedural success moreover, stent
placement is considered to have a favorable influnce on
early term mortality rates.
Key Words: Left main coronary
artery, Stenosis, Coroner angiography
Homocysteine is an amino acid present in the plasma and it
is regarded as a risk factor for the development of coronary
artery disease (CAD) by means of endothelial dysfunction.
Folat, vitamin B6 and vitamin B12 can decrease plasma
homocystein levels and improve endothelial dysfunction. The
association betvreen hyperhomocysteinemia and CAD or
restenosis after percutaneous coronary interventions and
vvhether decreasing plasma homocysteine levels can reduce
these risks remains controversial and different studies show
different results.
A case of
ascendent aortIc pseudoaneursym after perIcardIectomy
Emir M, Uncu H, Çağlı K, Altıntaş G, Şener E, Taşdemir O.
We
present a case of a 18-year-ald patient with a mass pulsatil
near the jugulum and had the sympthoms (eg; dispnea) 2 years
after pericardiectomy: because of constrictive pericarditis.
Physical examination findings was only
2/6° systolic sufl at the aortic localization. Diagnosis was
confirmed with the aid of two-dimensional echocardiography
annd aortography.a 8x8 cm diameter of pseudoaneursym at
anterior surface of ascending aorta and proxmity of tr.brachiocephalicus
vvhich had calcification around it was found by echo and
aortography.
We planed surgery for treatment. The
formation of a pseudoaneursym following pericardiectomy is a
rare complication. So we present this case report. Nowwe
know that, ascending aorta pseudoaneursym follovving
pericardiec¬tomy can be generated as a complication. VVe
suggest that a patient undergo pericardiectomy has to be
evaluated carefully because of pseudoaneursym formation.
Acute
coronary dıssectIon durIng coronary angIography lIkely due to
rapId dye InjectIon
Erikçi H, Gündüz H, Binak E, Akdemir R, Kanat M, Kurtoğlu N,
Keser N, Dindar İ, Uyan C.
Coronary artery dissections during coronary angiography are
rare. Prompt recognition and subsequent emergency
interventions are essential, especially when significant
amount of myocardium is threatened.
A new
technIque tor treatment of coronary musculer brıdge causıng
myocardıa IschemIa
Cin V.G, Pekdemir H, Akkuş N, Katırcıbaşı T.
Myocardial bridge is a congenital coronary anomaly vvhich
causes sudden cardiac death, cardiac arrythmias myocardial
ischemia and infarction. Recently, direct stent deployment
within myocardial bridges which cause serious ischemia is
getting vvidely used. İn this manuscript, primary stent
deployment and its result in a patient who has twc
symptomatic myocardial bridges in left anterior descending
artery is discussed below with literatüre.
The
frequency of anamolous origin of coronary arteries in
angiopgraphic series was reported 0,6%-1,6% Single coronary
artery is a rare congenital abnormality of the coronary
arteries where only one coronary artery arise from the
aortic trunk by a single coronary ostium, supplying the
entire heart. The incidence of single coronary artery
abnormalities varies between 0,024%-0,044% and particularly
Ula type is very rare. İn this article We present a case
with single coronary artery in vvhom coronary angiography
was normal and literatüre was reviewed.
Key Words: Coronary artery
abnormalities, Single coronary artery, Coronary angiography