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QuantItatIve angIographIc analysIs of
rIght ventrIcular global functIon In normal IncIdences and In
patIents wIth one-vessel coronary artery dIsease
Fettser D.V, Batyraliev T, Karben Z.A,
Preobrazhensky D.V, Sidorenko B.A, Avşar Ö.
At present right
ventriculography data can't be accurately estimated due to the absence of
software for quantitative analysis of the right ventricle (RV) volumes and
function. The aim of this study was to use existing software for left
ventriculography analysis to estimate right ventricular volumes and function
in patients without coronary lesions and in those with one-vessel coronary
artery disease (CAD). Thirty-eight patients without significant lesions of
coronary arteries and 27 patients with one-vessel CAD were examined with
left ventriculography and right atriography. Each examination was performed
in 2 projections: 30 right anterior oblique (RAO 30) and 60 left anterior
oblique (LAO 60) projections. Correction factor (CF) was obtained by finding
the ratio between stroke volumes of the left and right ventricles. The mean
CF was 0.924±0.289 for patients without CAD and 0.876±0.223 for patients
with one-vessel CAD. This method can be used for calculation of volume and
function RV by using existing software of quantitative angiographic analysis.
THE ASSOCIATION BETWEEN INSULIN
RESISTANCE AND FLOW MEDIATED DILATATION AND THE SEVERITY OF
CORONARY ATHEROSCLEROSIS IN NON-DIABETIC PATIENTS
Özcan T, Acele A, Çiçek D,
Çamsan A, Akkuş N, Yaşa E.M, Seyis S, Cin V.G.
Diyabeti
olamayan hastalarda insülin direnci ve akıma bağlı
dilatasyonun (AUV) birbiri ve koroner arteroskleroz ilişkisi
değerlendirmeyi amaçladık.
Çalışmamıza bilinen diyabeti olmayan ve koroner ajiyografi
endikasyonu alan 130 hasta alındı. İnsülin direncinin tanısı
için HOMA-IR indeksi
(The homeostasis model assessment insulin resistance index)
kullanıldı. Endotel disfonksiyonun değerlendirilmesi
amacıyla brakiyal arterde AUV bakıldı. Koroner arter
hastalığının yaygınlığının değerlendirilmesi amacıyla
Gensini Skoru kullanıldı.
Brakiyal
arter AUV ile koroner arter hastalığının yaygınlığı arasında
negatif korelasyon izlenirken endotelden bağımsız
vasodilatasyon (EBV) ile
anlamlı korelasyon gözlenmemiştir (r=-0,286, p=0,001;
-0,095, p=0,282). HOMA-IR değerleri ile koroner arter
hastalığı yaygınlığı arasında istatiksel olarak anlamlı
ilişki saptanmamıştır (p=0,187). HOMA-IR >1,8 ve HOMA-IR
>1,8 olarak hastalar iki gruba ayrıldığında, AUV açısından
istatiksel olarak anlamlı farklılık gözlendi (6,6-4,2,
p=0,001). Koroner arter hastalığının yaygınlığının
değerlendirilmesi amacıyla HOMA-IR değerlerinin herhangi bir
tanısal değeri saptanmamışken, endotel disfonksiyonuna neden
olarak akıma bağlı vasodiltasyonu azalttığı gösterilmiştir.
Key Words: HOMA-IR, Akıma bağlı dilatasyon(AUV),
Endotel disfonksiyonu.
ComparIson of carotId IntIma-medIa thIckness and
effectIng factors In hemodIalysIs and perItoneal dIalysIs patIents
İnal A, Kayrak M, Atalay
H, Kaya C, Güney İ, Akıllı H, Arı H, Türk S.
Cardiovascular
diseasesare the most important reason of morbidity and
mortality in renal replacement theraphy patients. Carotid
intima-media thickness (CIMT) is also predictor of
cardiovascular diseases. In this study, we compared CIMT and
related factors in hemodialysis (HD) and peritoneal dialysis
(PD) patients.
The study group included 40 HD and 40 PD (totally 80
patients) patients who admitted our clinic. Homocysteine
levels, inflamatory markers (serum CRP, ferritin and
fibrinogen levels), serum albumin levels and CIMT are
measured in study group. Additionally lipid parameters (Lp(a),
HDL, LDL, total cholestrol and triglyceride levels), calcium,
phosphorus, parathormone levels are measured. Body mass
indexes were calculated.
CIMT in HD patients was greater than PD patients (1,54±0,29,
1,31±0,24, p=0,001). There was a positive correlation
between CIMT and age/CRP (r=0,38, p=0,001 and r=0,29,
p=0,008), strong negative correlation between CIMT and
albumin levels (r=-0,79, p=0,001). Also there was negative
correlation between dialysis efficiancy and CIMT (r=-0,24,
p=0,024). There were no demographical differences between
groups.
The greater CIMT in HD patients shows increased coronary
artery disease risk. The relationship between increased CIMT
and high CRP level/low albumin level in these patient group
is also interesting. These parameters are important and
beneficial in risk stratification and follow up of these
patients.
HomocysteIne total cholesterol-hIgh
densIty lIpoproteIn ratIo for evaluatIon of coronary artery dIsease
Kayrak M, Ayhan S.S, Doğan
M, Bacaksız A, Turan Y, Kaya Z, Gök H, Baysal B.
In this study, we aimed to evaluate
association between homocysteine-total cholesterol/HDL (TC/HDL) ratio and
presence and extension of coronary artery disease (CAD). We detected
usefulness of TC/HDL ratio instead of homocysteine.
Study group consist of 83 patients (58 acute coronary syndrome, 25 stable
angina pectoris) and 25 subjects as a control group that have normal
coronary arteries. More than %50 stenosis of coronary arteries indicate
coronary artery disease. Modified Gensini’s score (MGS) was used to reflect
the extent of coronary atherosclerosis. Level of homocysteine, high
sensitivity CRP (hsCRP) and serum lipids were measured in all groups. TC/HDL
ratio was calculated.
Homocysteine and TC/HDL ratio are higher than the control group as a
independent predictor for CAD. There is no correlation between MGS and
homocysteine and TC/HDL ratio (r=0,1 p=0,3/r=0,11 p=0,3 respectively). hsCRP
and MGS in the highest TC/HDL quartile are higher than other quartiles.
Level of homocysteine and TC/HDL ratio are similar in acute coronary
syndrome and stable angina pectoris patients. Although level of homocysteine
is similar in the diabetics and non-diabetic patients, TC/HDL ratio is
significantly higher in diabetic patients.
Homocysteine and TC/HDL ratio are independent predictors of CAD. Because of
no relationship between homocysteine and extension of CAD and conflicting
data about homocysteine lowering therapy, we think that detection of TC/HDL
ratio and lowering this ratio is beneficial for CAD.
Key Words: Coronary artery disease, Total cholesterol/high density
lipoprotein ratio, Homocysteine, Modified Gensini’s score
InterventIonal therapy at coronary bIfurcatIon lesIon
Akpınar O, Batyraliev T.
Bifurcation
lesion is complex lesion; it has a lower procedural sucsess
rate and a high risk of restenosis. Interventional therapy
at this lesion is used two diffirent procedur; single vessel
stenting and side branch angioplasty or dual stenting of the
main vessel and side branch. Recently, new data are appeared
with use of drug eluting stent. In this review, we discuss
succession the use of bare metal or drug eluting stent, one
or two stent at bifurcation lesion.
ArrhythmogenIc rIght ventrIcular cardIomyopathy
and epsIlon wave
Çağlı K, Duyuler S, Özcan F, Gölbaşı
Z.
Arrhythmogenic right
ventricular cardiomyopathy (ARVC) is an inherited
cardiomyopathy that primarily involves right ventricle (RV).
Histologically it is characterized by fibrofatty replacement
of the myocardium and clinically it presents with RV
dysfunction and ventricular arrhythmias. One of the major
diagnostic criteria, epsilon wave is present in up to 30% of
ARVC patients' surface electrocardiogram. In this report we
discuss a case of a young male patient, who presents with
ventricular tachycardia and epsilon wave.
Key Words: Arrhymogenic right ventricular
cardiomyopath, Epsilon wave
ClInIcal and angIographIc characterIstIcs of the
subjects wIth coronary artery fIstulae
Yavuzkır M, Özbay Y,
Erdem K, Polat V, Dağlı M.N, Karaca I.
Coronary artery fistulae (CAF)
are rare, coronary anomalies that are difficult to detect.
They are usually congenital. The most frequent symptom is
chest pain that is due to distal coronary stealing syndrome.
If not treated, serious complications many occur. In this
article, we have reported the clinical and angiographic
characteristics of the subjects with CAF in our clinic.
A dIfferent approach to coronary artery
perforatIon
Biçer A, Akdemir R, Kılıç
H, Doğan M, Balcı M, Sarı M.
Coronary
artery perforation is a rare but serious complication of
percutaneous coronary interventions. Prompt decision-making
following diagnosis is of key importance. Whether to perform
prolonged attempts at percutaneous repair or to promptly
refer the patient for emergency surgery soon after diagnosis
still remains a matter of debate. In this report we report
the case of a 63-year-old man suffering from coronary artery
perforation during left anterior descending coronary artery
percutaneous transluminal coronary angioplasty-stenting, who
underwent subsequent a successful emergency surgery.
Key Words:
Coronary perforation, Covered stents, Emergency surgery
